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Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration
5 µM concentration in vitro and in cellular assays
It acts as a selective
MERcK-5 (P6) is shown to inhibit kinase by interacting within the ATP-binding cleft of each JAK
Molecular Weight: 436
DY-131 - CAS# 95167-41-2 60200 Inhibition of the prostaglandin-degrading enzymeDY131, also known as GSK 9089, CAS No. 95167 41 2, is a novel selective agonist at estrogen related receptors ERR and ERR. DY131 could potentiate the ERRgamma induced growth inhibition in LNCaP ERRgamma and DU145 ERRgamma cells in a dose dependent manner. ERRgamma may perform an antiproliferative or tumor suppressing function in prostate cancer cells. ERRgamma could be a novel therapeutic target for prostate cancer treatment. Product information CAS
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