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15-18H2/b24-23-
Ehrlich LS
740 Y-P (30 μM
LY487379 hydrochloride potentiates glutamate-stimulated [35S]GTPγS binding with EC50 values of 1
InChiKey: CQTLHLYDQYOEJW-FIBGUPNXSA-N
TAK-960 monohydrochloride 9-4603 15-18H2/b24-23-TAK 960 monohydrochloride is an orally available, selective inhibitor of polo like kinase 1 (PLK1), with an IC50 of 0. 8 nM. TAK 960 monohydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16. 9 and 50. 2 nM, respectively. TAK 960 monohydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts. Product information CAS Number: 2108449 45 0
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