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5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-(4-((5-(2-(2
Smiles: CC(C)C(NC(=O)C1C=CC2=CC=CC=C2N=1)C(=O)NC(CC(O)=O)C(=O)COC1=C(F)C=CC=C1F
Formula: C35H58O9
CAS Number: 55-98-1
with MICs that range from 1 to 2 μg/ mL
Lappaconitine myl)-lysine 5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-(4-((5-(2-(2Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as analgesic principle. IC50 value: Target: In vitro: In vivo: Lappaconitine was characterized as analgesic principle by our laboratory. The results suggest that lappaconitine can produce analgesia, possibly through a decrease in cellular calcium availability and PAG may be involved in the Ca2+ antagonistic effect on lappaconitine analgesia . Changes in lappaconitine levels in
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