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4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-ylium
Erpenbeck VJ
4-hydroxytamoxifen analog
which is greater than 20-fold selectivity over CK1δ (IC50
Lysine acetyltransferase HBO1 (KAT7) inhibitor
Acitretin Size:Solid 10 mg 4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-yliumAcitretin is an oral synthetic retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate (sc 205689). It has demonstrated an ability to suppress the development of chemically induced epithelial tumors, as well as squamous cell carcinoma. Acitretin has potential antineoplastic, chemopreventive, anti psoratic, and embryotoxic properties. Acitretin activates nuclear retinoic acid receptors (RAR), resulting in induction of
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