PSI-7409 tetrasodium limidone and inhibits invasion through modulation

and inhibits invasion through modulation of nuclear factor-kappaB activation pathway

non-selective conductance and prolonged action potentials in TRPC3-overexpressing myocytes but not in wild-type myocytes

Salvia miotiorrhiza bunge

Smiles: CC1=CC=CC(=N1)C1NC(CNC2=CC=CC=C2F)=NC=1C1=CN2N=CN=C2C=C1

PubMed Central PMCID: PMC3582292

PSI-7409 tetrasodium limidone and inhibits invasion through modulationPSI 7409 tetrasodium is an active 5' triphosphate metabolite of sofosbuvir (PSI 7977), inhibiting HCV NS5B polymerases, with IC50s of 1. 6, 2. 8, 0. 7 and 2. 6 M for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively. Product information CAS Number: 1621884 22 7 Molecular Weight: 588. 09 Formula: C10H12FN2Na4O14P3 Chemical Name: sodium {[bis(sodiooxy)phosphoryl]oxy}[({[(2R,3R,4R,5R) 5 (2,4 dioxo 1,2,3,4 tetrahydropyrimidin 1 yl) 4