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2-(3-(1H-Indazol-5-yl)ureido)-5-(tert-butyl)thiophene-3-carboxylic acid
a downstream substrate of the MEK5/ERK5 signaling cascade
The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channels
4-16H2/t18-/m1/s1
InChi: InChI=1S/C19H16F2N8O2/c1-31-19(30)25-14-15(22)26-17(27-16(14)23)13-11-6-10(20)7-24-18(11)29(28-13)8-9-4-2-3-5-12(9)21/h2-7H
Carmustine Catalog No.:M9844-10 2-(3-(1H-Indazol-5-yl)ureido)-5-(tert-butyl)thiophene-3-carboxylic acidCarmustine is antineoplastic nitrosourea. Carmustine alkylates and cross links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood brain barrier readily. Product information CAS Number: 154 93 8 Molecular Weight: 214. 05