5, 15-DPP Size:Contact [email protected] for quotation VNP significantly increases the intracellular

VNP significantly increases the intracellular levels of cGMP

CAS Number: 477-30-5

InChi: InChI=1S/C10H16N2O5S/c13-8(14)4-2-1-3-7-9-6(5-18(7

59(4):1410-24

CAS Number: 159997-94-1

5, 15-DPP Size:Contact [email protected] for quotation VNP significantly increases the intracellular5,15 diphenylporphyrin (5,15 DPP) is a selective STAT3 SH2 antagonist . Stat3 is constitutively activated in many human cancers. Stat3 functions as a critical mediator of oncogenic signaling through transcriptional activation of genes encoding apoptosis inhibitors, cell cycle regulators and inducers of angiogenesis . Aberrant STAT3 activity has been associated with transforming mechanisms induced by oncogenic tyrosine kinases . In vitro: 5,15 DPP