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4-dioxobutan-2-yl)-3-((S)-2-(3-(tert-butyl)ureido)-3
12-dihydro-9-nitro-indolo[3
26)17-7-4-15(21)5-8-17/h2-5
It is also an endogenous active metabolite and analogue of the neurotransmitter γ-aminobutyric acid (GABA)
Mycophenolic acid D3 (Mycophenolate D3) is deuterium labeled Mycophenolic acid
Dihydrosanguinarine rtmannin 4-dioxobutan-2-yl)-3-((S)-2-(3-(tert-butyl)ureido)-3Dihydrosanguinarine is an alkaloid and a metabolite of the alkaloid sanguinarine that has diverse biological activities, including anticancer, fungicidal, and antiprotozoal properties. It inhibits proliferation of PANC 1, SW 1990, and HPDE6c7 cancer cells when used at concentrations of 10, 20, and 30 M. It also reduces the levels of phosphorylated ERK and C RAF, halts the cell cycle at the G0 G1 and G2 M phases, and induces apoptosis in PANC 1 cells.
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