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Smiles: CC1=CN=C(C=N1=O)C(O)=O
3)11-4-7-13(8-5-11)18-14-9-6-12(16)10-17-14/h4-10H
Odanacatib also shows weak inhibition of the processing of the MHC II invariant chain protein Iip10 in mouse splenocytes compared to LHVS (minimum inhibitory concentration 1-10 μM versus 0
Williams LM
N-dimethyl-2
PF-04217903 (methanesulfonate) medil Hydrochloride Smiles: CC1=CN=C(C=N1=O)C(O)=OPF 04217903 is a MET tyrosine kinase inhibitor, is also a n orally bioavailabe, small molecule tyrosine kinase inhibitor of the proto oncogene c Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c Met inhibitor PF 04217903 selectively binds to and inhibits c Met, disrupting the c Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction