ZLJ-6 Size:Contact [email protected] for quotation Smiles: CC1C(=NNC=1CC)C(=O)NC1=CC=C(C=C1)[C@H]1CNCCO1

Smiles: CC1C(=NNC=1CC)C(=O)NC1=CC=C(C=C1)[C@H]1CNCCO1

Reduces heart rate

CAS Number: 73360-56-2

At high concentrations

InChiKey: PYFRREJCFXFNRR-UHFFFAOYSA-N

ZLJ-6 Size:Contact [email protected] for quotation Smiles: CC1C(=NNC=1CC)C(=O)NC1=CC=C(C=C1)[C@H]1CNCCO1IC50: 0. 73, 0. 31, and 0. 99 M for COX 1, COX 2, and 5 LO, respectively ZLJ 6 is a dual inhibitor of COX and 5 lipoxygenase (5 LO). Cyclooxygenase (COX) is an enzyme that is responsible for formation of prostanoids, such as thromboxane and prostaglandins such as prostacyclin. 5 lipoxygenase (5 LO) is the major source of leukotrienes. In vitro: ZLJ 6 was identified as a potent inhibitor of cyclooxygenase in human whole blood. It also inhibited the