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Macitentan is a dual ERA
47)22-11-12-22)39-28(42)25-15-21(49-29-24-14-20(36)10-13-23(24)26(48-8)17-37-29)18-41(25)30(43)27(33(2
3-benzodiazol-6-yl]-1H-1
OC(=O)CCCC1C=CC=CC=1 |^1:0|
PI-103 inhibits constitutive and growth factor-induced PI3K/Akt
Betulinic acid - CAS# 472-15-1 Catalog No.:M10557-10 Macitentan is a dual ERABetulinic acid is a pentacyclic lupane type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) with antiinflammatory, anti HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic
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