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a guanidine derivative
Water: 76 mg/mL(200
Compound Example 7
Cesium Chloride (12 mg/100 g body weight
9 μM and 0
MPI-0441138 Catalog No.:M22439-C a guanidine derivativeEC50: 2 nM for caspase activation MPI 0441138 is an inducer of apoptosis and growth inhibition. Apoptosis or programmed cell death is a process that organisms use to eliminate excessive cells and to control cell numbers. Caspases, a family of cysteine proteases, plays a critical role for the initiation as well as execution of apoptosis. In vitro: MPI 0441138 was identified as a highly active inducer of apoptosis and as a potent inhibitor of cell