Plinabulin Catalog No.:M10736-2 administration is less than 10

administration is less than 10 min

InChiKey: FWIVDMJALNEADT-SFTDATJTSA-N

Smiles: [O-][N+](=O)C1C=CC(=CC=1)C1=CC=C(/C=C2\C=C(C3C=CC=CC=3)N(C3C=CC(=CC=3)C(O)=O)C\2=O)O1

Smiles: CC1=CC(NC2=CC=C(F)C(C[C@@]3(C[C@@H](C)N(CC3)CC3=CC=CC(Cl)=C3F)C(O)=O)=N2)=NN1

Smiles: CC[C@H](NC(=O)[C@H](CS(=O)(=O)CC1CC1)N[C@@H](C1=CC=C(F)C=C1)C(F)(F)F)C(=O)C(=O)NC1CC1

Plinabulin Catalog No.:M10736-2 administration is less than 10MBRI 001 is a deuterium substituted plinabulin derivative as a potent anti cancer agent. MBRI 001 exhibited better pharmacokinetic characteristics than that of plinabulin. Additionally, its antitumor activity is in a low nanomolar level for a variety of cancer cell lines and high activity against human NCI H460 xenograted in mice intravenous administration. Importantly, continuous administration of MBRI 001 exhibited lower toxicity compared to