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InChi: InChI=1S/C20H13N3O/c24-20-17-12(9-21-20)15-10-5-1-3-7-13(10)22-18(15)19-16(17)11-6-2-4-8-14(11)23-19/h1-8
Chemical Name: 9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acid
Solubility: DMSO : 100 mg/mL (276
Formula: C17H18N4O2
Inhibitory activity of apogossypol in human prostate cancer in vitro and in vivo
FD-IN-1 eceptor antagonists-2 InChi: InChI=1S/C20H13N3O/c24-20-17-12(9-21-20)15-10-5-1-3-7-13(10)22-18(15)19-16(17)11-6-2-4-8-14(11)23-19/h1-8FD IN 1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD IN 1 also inhibits factor XIa (FXIa) and Tryptase 2 with IC50s of 7. 7 and 6. 5 M, respectively. Product information CAS Number: 1646682 14 5 Molecular Weight: 377. 43 Formula: C23H23NO4 Chemical Name:
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