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Chemical Name: 2-(4-{[(2R)-2-aminobutyl]amino}pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride
BS-181 dihydrochloride (0-50 μM
potency and selectivity of Oclacitinib is determined against JAK family members and cytokines that trigger JAK activation in cells
Epub 2017 Feb 10
Chemical Name: (E)-N-[trans-3-{1-(2-Nitrophenyl)-1H-pyrrol-2-yl} allylidenamino]guanidinium acetate
AHR antagonist 5 osylvisamminol Chemical Name: 2-(4-{[(2R)-2-aminobutyl]amino}pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochlorideAHR antagonist 5, a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018195397, example 39, has an IC50 of < 0. 5 . AHR antagonist 5 significantly inhibits tumor growth combined with checkpoint inhibitor anti PD 1. Product information CAS Number: 2247953 39 3 Molecular Weight: 550. 89 Formula: C25H27Cl3FN7 Chemical Name: (3R) N [2 (5 fluoropyridin 3 yl) 8 (propan 2 yl)pyrazolo[1,5 a][1,3,5]triazin 4 yl]
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