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Inhibits Interleukin 17 Production and Ameliorates Collagen-Induced Arthritis in Mice and Cynomolgus Monkeys
InChiKey: WDEKUGNKKOGFOA-UHFFFAOYSA-N
PubMed PMID: 29293331
5-g]quinoxalin-6-yl)phenyl]methyl]piperidin-4-yl]-1H-benzimidazol-2-one
and inhibition of ERK1/2 and p90RSK phosphorylation
AMPK activator 4 20975 Inhibits Interleukin 17 Production andAMPK activator 4 is a potent AMPK activator without inhibition of mitochondrial complex I. AMPK activator 4 selectively activates AMPK in the muscle tissues. AMPK activator 4 dose dependently improves glucose tolerance in normal mice, and significantly lowers fasting blood glucose level and ameliorates insulin resistance in db db diabetic mice. Anti hyperglycemic effect. Product information CAS Number: 2493239 46 4 Molecular Weight: 420. 89 Formula:
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