BI-749327 oglutaric acid CH4O3S/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13

Name: BI-749327 oglutaric acid CH4O3S/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13
Brand: neuraldrones.de
SKU: 83432472163
Price: 122.00 USD
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SKU: 83432472163

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Description

CH4O3S/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13

3*1-5(7)4-6(2)3/h2-4

Treatment with PXS-5153A causes a significantly reduction in HYP compared to the CCl4 group

4′-THIF-treated group

16-diazatricyclo[14

BI-749327 oglutaric acid CH4O3S/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13BI 749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI 749327 is 85 fold more selective for mouse TRPC6 than TRPC3 and 42 fold versus TRPC7. Product information CAS Number: 2361241 23 6 Molecular Weight: 442. 43 Formula: C23H21F3N4O2 Chemical Name: 6 (1 {4 [4 (trifluoromethyl)phenoxy]benzoyl}piperidin 4 yl)pyridazin 3 amine Smiles:

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