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IC50 value: Target: Maxacalcitol (22-Oxacalcitriol)suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo
CAS Number: 33286-22-5
and the combination of SMI-4a and a mitogen-activated protein kinase kinase 1/2 (MEK1/2) inhibitor was highly synergistic in killing pre-T-LBL cells
Formula: C13H14ClN3O2
is a toxin payload in antibody drug conjugates (ADCs)
GNE-207 P7-4 IC50 value: Target: Maxacalcitol (22-Oxacalcitriol)suppressesGNE 207 is a potent, selective and orally bioavailable inhibitor of the bromodomain of CBP, with an IC50 of 1 nM, exhibits a selectively index of >2500 fold against BRD4 (1). GNE 207 shows excellent CBP potency, with an EC50 of 18 nM for MYC expression in MV 4 11 cells. Product information CAS Number: 2158266 58 9 Molecular Weight: 510. 59 Formula: C29H30N6O3 Chemical Name: 5 {8 [5 acetyl 1 (oxan 4 yl) 1H,4H,5H,6H,7H pyrazolo[4,3 c]pyridin 3
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