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AI-10-47 144PEG6-NHS ester TGFβRI-IN-1 is an oral active

SKU: 83476075623

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Description

TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor

3-3 mg/kg) dose-dependently decreases plasma levels of these all parameters

1]nonan-3-yl}-1H-indazole-3-carboxamide hydrochloride

InChi: InChI=1S/C18H30N2O5/c1-6-14(7-2)25-16-10-13(18(23)24-8-3)9-15(19-11(4)21)17(16)20-12(5)22/h10

Lin28-let-7a antagonist 1 (compound 1) shows a clear antagonistic effect against the Lin28A-let-7a-1 interaction with an IC50 of 4

AI-10-47 144PEG6-NHS ester TGFβRI-IN-1 is an oral activeAI 10 47 is a small molecule inhibitor of CBF RUNX binding, with an IC50 of 3. 2 M. Product information CAS Number: 1256094 31 1 Molecular Weight: 279. 22 Formula: C13H8F3N3O Chemical Name: 2 (pyridin 2 yl) 6 (trifluoromethoxy) 1H 1,3 benzodiazole Smiles: FC(F)(F)OC1=CC2NC(=NC=2C=C1)C1=CC=CC=N1 InChiKey: JSNWHSDKJSOXET UHFFFAOYSA N InChi: InChI=1S C13H8F3N3O c14 13(15,16)20 8 4 5 9 11(7 8)19 12(18 9)10 3 1 2 6 17 10 h1 7H,(H,18,19) Technical Data

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