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DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor
Linezolid shows excellent in vitro activity against all the strains tested (MICs ≤ 1 μg/ml)
ADAM17 inhibition enhances platinum efficiency in ovarian cancer
with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line
PubMed PMID: 28400256
CA-5f - CAS# 1370032-19-1 Catalog No.:M12459-2 DM3 (Maytansinoid DM3) is aCA 5f is a potent late stage macroautophagy autophagy inhibitor via inhibiting autophagosome lysosome fusion. CA 5f increases LC3B II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti tumor activity. Product information CAS Number: 1370032 19 1 Molecular Weight: 388. 46 Formula: C24H24N2O3 Chemical Name: (3E, 5E) 3 [(3, 4 dimethoxyphenyl)methylidene] 5 [(1H indol 3 yl)methylidene] 1 methylpiperidin 4 one
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