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Reversine Catalog No.:M10364-10 Solubility: DMSO: 71 mg/mL (185

SKU: 84198940743

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Description

Solubility: DMSO: 71 mg/mL (185

InChi: InChI=1S/C17H12N2O6S2

CCCCC1OC2=CC=CC=C2C=1C(=O)C1=CC(I)=C(OCCN(CC)CC)C(I)=C1

C2HF3O2/c18-12-2-1-10(19)7-13(12)28-11-3-5-24(6-4-11)15-8-14(29-22-15)17-20-23-25(21-17)9-16(26)27

1093/biolre/iox048

Reversine Catalog No.:M10364-10 Solubility: DMSO: 71 mg/mL (185Reversine is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation. Reversine is also a novel Aurora kinases inhibitor that inhibits colony formation of human acute myeloid leukemia cells. Reversine inhibits the phosphorylation of histone H3, a direct downstream target of Aurora kinases. Similarly to the Aurora kinase inhibitor VX 680, reversine inhibited colony formation of leukemic cells from patients with

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