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VU0071063 (0~20 μM
InChiKey: YRFRBTOMOUXLRJ-UHFFFAOYSA-M
SC144 hydrochloride shows potent inhibition of gp130 ligand-triggered signaling
Smiles: CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)NCC1C=CC=CC=1
FD223 (20 and 40 mg/kg
BSJ-04-132 l milnacipran-d5 VU0071063 (0~20 μMBSJ 04 132 is a potent and selective Ribociclib based CDK4 degrader (PROTAC), with IC50s of 50. 6 nM and 30 nM for CDK4 D1 and CDK6 D1, respectively. BSJ 04 132 does not induce CDK6 and IKZF1 3 degradation. BSJ 04 132 has anti cancer activity. Product information CAS Number: 2349356 39 2 Molecular Weight: 819. 91 Formula: C42H49N11O7 Chemical Name: 7 cyclopentyl 2 [(5 {4 [4 (2 {[2 (2,6 dioxopiperidin 3 yl) 1,3 dioxo 2,3 dihydro 1H isoindol 4
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