(R)-ADX-47273 nylacetate increasing the behavioural effects of

increasing the behavioural effects of hallucinogenic drugs in animal tests

It inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression

PHA-767491 in combination with 5-FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP-Ribose) polymerase fragmentation in HCC cells

2004 Sep 1

CZC-54252 is a potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) with IC50 values 1

(R)-ADX-47273 nylacetate increasing the behavioural effects of(R) ADX 47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . Product information CAS Number: 851881 59 9 Molecular Weight: 369. 36 Formula: C20H17F2N3O2 Chemical Name: (3R) 1 (4 fluorobenzoyl) 3 [3 (4 fluorophenyl) 1,2,4 oxadiazol 5 yl]piperidine Smiles: O=C(C1C=CC(F)=CC=1)N1C[C@@H](CCC1)C1=NC(=NO1)C1C=CC(F)=CC=1 InChiKey: VXQCCZHCFBHTTD OAHLLOKOSA N InChi: InChI=1S C20H17F2N3O2 c21 16 7 3 13(4 8 16)18 23