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Loss-of-function of MTH1 impaired growth of KRAS tumor cells
is a potent and selective small molecule antagonist of melanopsin-mediated photo-transduction (IC50~160 nM)
13(15 Pt 1):4538-46
NU7026 (10 μM) potentiates ionizing radiation (IR) cytotoxicity [potentiation factor at 90% cell kill (PF90)=1
InChiKey: JUWDSDKJBMFLHE-UHFFFAOYSA-N
MDL-29951 - CAS# 130798-51-5 size:2mg solid Loss-of-function of MTH1 impaired growthMDL 29951, CAS No. 130798 51 5, is a novel glycine antagonist of NMDA receptor activation, with Ki of 0. 14 M for [3H]glycine binding in vitro and in vivo. Product information CAS Number: 130798 51 5 Molecular Weight: 302. 11 Formula: C12H9Cl2NO4 Chemical Name: 2 Carboxy 4,6 dichloro 1H indole 3 propanoic acid Smiles: OC(=O)CCC1=C(NC2=CC(Cl)=CC(Cl)=C12)C(O)=O InChiKey: KNBSYZNKEAWABY UHFFFAOYSA N InChi: InChI=1S C12H9Cl2NO4 c13 5 3 7(14)10 6(1 2