Foretinib 603oglibose Smiles: C[C@@H]1CC=CC=CC=CC=C[C@@H](C[C@@H]2O[C@@](O)(C[C@H](O)[C@H]2C(O)=O)C[C@@H](O)C[C@H]2O[C@@H]2C=CC(=O)O1)O[C@@H]1O[C@H](C)[C@@H](O)[C@H](N)[C@@H]1O |t:3

Smiles: C[C@@H]1CC=CC=CC=CC=C[C@@H](C[C@@H]2O[C@@](O)(C[C@H](O)[C@H]2C(O)=O)C[C@@H](O)C[C@H]2O[C@@H]2C=CC(=O)O1)O[C@@H]1O[C@H](C)[C@@H](O)[C@H](N)[C@@H]1O |t:3

GS5734-metabolite

CAS Number: 183232-66-8

Smiles: OP(O)(=O)CN1C2=CC(=C(C=C2NC(=O)C1=O)C(F)(F)F)N1CCOCC1

Formula: C20H22N8O5

Foretinib 603oglibose Smiles: C[C@@H]1CC=CC=CC=CC=C[C@@H](C[C@@H]2O[C@@](O)(C[C@H](O)[C@H]2C(O)=O)C[C@@H](O)C[C@H]2O[C@@H]2C=CC(=O)O1)O[C@@H]1O[C@H](C)[C@@H](O)[C@H](N)[C@@H]1O |t:3Foretinib, also known as XL880 and GSK1363089, is an orally bioavailable small molecule with potential antineoplastic activity. MET VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto oncogene c MET has been found to be over