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17-tetramethyl-11-oxo-9-{[(2S
NVP-BEZ235 and NVP-BGT226
InChiKey: LAZPBGZRMVRFKY-HNCPQSOCSA-N
CAS Number: 566914-00-9
Chemical Name: 2-[(5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1
Emricasan Catalog No.:M10978-10 17-tetramethyl-11-oxo-9-{[(2SEmricasan, also known as IDN 6556 and PF 03491390, is a first in class caspase inhibitor in clinical trials for the treatment of liver diseases. Emricasan (IDN 6556) decreases liver injury and fibrosis in a murine model of non alcoholic steatohepatitis. IDN6556 facilitates marginal mass islet engraftment in a porcine islet autotransplant model. Oral IDN 6556 may lower aminotransferase activity in patients with chronic hepatitis C. Orally administered