isolated from the sclerotium of Poria cocos
It allosterically binds (Kd 10-30 nmol/L) to the regulatory Zn(2+) binding domain of HDAC4 that locks the protein in a conformation preventing HDAC4/N-CoR/HDAC3 complex formation
on dextran sulfate sodium-induced colonic inflammation through capsaicin-sensitive afferent neurons in rats
12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h3-5
3)28-18(23)4-10-24-12-14-26-16-17-27-15-13-25-11-7-20(5-8-21)6-9-22/h21-22H
5’-[(Desloratadine)methyl] Rupatadine-d8 Catalog No.:M26414-C isolated from the sclerotium ofProduct information CAS Number: 1794669 33 2 Molecular Weight: 732. 81 Formula: C45H43Cl2N5 Chemical Name: 13 chloro 2 [1 ({5 [(4 {13 chloro 4 azatricyclo[9. 4. 0. 0,]pentadeca 1(15),3,5,7,11,13 hexaen 2 ylidene}(2,2,6,6 H)piperidin 1 yl)methyl]pyridin 3 yl}methyl)(2,2,6,6 H)piperidin 4 ylidene] 4 azatricyclo[9. 4. 0. 0,]pentadeca 1(15),3,5,7,11,13 hexaene Smiles: