PF-04957325 Catalog No.:M20193-C 3)4)58-39(61)8-6-7-17-55-42(62)32(22-54)18-29-11-16-37(38(19-29)65-5)66-25-31-14-15-33(46(48

Name: PF-04957325 Catalog No.:M20193-C 3)4)58-39(61)8-6-7-17-55-42(62)32(22-54)18-29-11-16-37(38(19-29)65-5)66-25-31-14-15-33(46(48
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SKU: 88198025433
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Description

3)4)58-39(61)8-6-7-17-55-42(62)32(22-54)18-29-11-16-37(38(19-29)65-5)66-25-31-14-15-33(46(48

J J Bright

ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro

1432597-26-6

28(6):786-90

PF-04957325 Catalog No.:M20193-C 3)4)58-39(61)8-6-7-17-55-42(62)32(22-54)18-29-11-16-37(38(19-29)65-5)66-25-31-14-15-33(46(48PF 04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0. 7 nM and 0. 3 nM for PDE8A and PDE8B, respectively. Product information CAS Number: 1305115 80 3 Molecular Weight: 400. 38 Formula: C14H15F3N8OS Chemical Name: 3 {[(2R) 4 [(1,3 thiazol 2 yl)methyl]morpholin 2 yl]methyl} 5 (trifluoromethyl) 3H [1,2,3]triazolo[4,5 d]pyrimidin 7 amine Smiles: NC1=NC(=NC2=C1N=NN2C[C@H]1CN(CC2=NC=CS2)CCO1)C(F)(F)F InChiKey: VNLPYEMGHGDRRZ

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