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08 μM for HDAC3 and displays no effective inhibition of any other HDAC at concentrations up to 15 μM
ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24
51(1):17-20
which promotes differentiation of hESCs/iPSCs to cardiomyocytes when used at the second stage of differenitation
Preclinical studies indicate that LX7101 significantly reduced intraocular pressure in both mouse and monkey models
SR-3306 HA-665752 08 μM for HDAC3 andSR 3306 is an aminopyrimidine JNK inhibitor. SR 3306 reduces the loss of dopaminergic cell bodies in the SNpc and their terminals in the striatum produced by unilateral injection of 6 hydroxydopamine (6 OHDA) into the nigrostriatal pathway. Product information CAS Number: 1128096 91 2 Molecular Weight: 490. 56 Formula: C28H26N8O Chemical Name: N {4 [3 (6 methylpyridin 3 yl) 1H 1,2,4 triazol 1 yl]phenyl} 4 [3 (morpholin 4 yl)phenyl]pyrimidin 2 amine
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