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IC87114 (5 µM) potently inhibits N-formyl-methionyl-leucyl-phenylalanine (fMLP)-stimulated phosphatidylinositol triphosphate (PIP3) biosynthesis and chemotaxis
and IL-6 productions in RAW 264
are inoculated into NOD/SCID mice by subcutaneous injection
selective and orally bioavailable ROCK1 inhibitor (IC50=7 nM)
activates apoptosis
BIO-013077-01 Catalog No.:M15123-2 IC87114 (5 µM) potently inhibitsBIO 013077 01 is a pyrazole TGF inhibitor. Product information CAS Number: 746667 48 1 Molecular Weight: 287. 32 Formula: C17H13N5 Chemical Name: 6 [3 (6 methylpyridin 2 yl) 1H pyrazol 4 yl]quinoxaline Smiles: CC1=CC=CC(=N1)C1=NNC=C1C1C=C2N=CC=NC2=CC=1 InChiKey: VXJLYXCHOKEODY UHFFFAOYSA N InChi: InChI=1S C17H13N5 c1 11 3 2 4 15(21 11)17 13(10 20 22 17)12 5 6 14 16(9 12)19 8 7 18 14 h2 10H,1H3,(H,20,22) Technical Data Appearance: Solid Power Purity: