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as a less expensive alternative
Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney
GSK 2251052
Smiles: CNCCCOC1=CC(F)=C(C2C(Cl)=NC3=NC=NN3C=2N[C@@H](C)C(F)(F)F)C(F)=C1
Smiles: N#CC1C=C(N=CC=1)N1[C@@H](CCC1=O)C(=O)N(C(C1=CC=CC=C1Cl)C(=O)NC1CC(F)(F)C1)C1=CC(F)=CN=C1
Dynasore - CAS# 304448-55-3 coxib D4 as a less expensive alternativeDynasore is a dynamin inhibitor (IC50 = 15 M). dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts. Dynasore disrupts trafficking of herpes simplex virus proteins. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis independent NF B activation. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. Dynasore impairs cholesterol
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