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Hongwei & Li
which may be mediated by ABCG2
1374598-80-7
Chemical Name: 2-chloro-N-{[2'-(cyanosulfamoyl)-[1
The IC50 values for Acoziborole in these assays are all above 10 µM
PT 1 Catalog No.:M23080-C Hongwei & LiPT 1 is a selective activator of AMPK with EC50 value of 0. 3 M for AMPK 111 . AMP activated protein kinase (AMPK) is serine threonine protein kinase that involved in cellular energy homeostasis and acts as an energy sensor. AMPK is a heterotrimer and increases ATP generation . PT 1 is a selective AMPK activator. PT1 activated human AMPK 1394, AMPK 2398 and AMPK(111) with EC50 values of 8, 12 and 0. 3 M, respectively. PT1 exhibited maximum activity
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