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Hexaminolevulinate hydrochloride - CAS# 140898-91-5 60022 PubMed Central PMCID: PMC2849388

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Description

PubMed Central PMCID: PMC2849388

hydrolysis

Biochemistry

PubMed PMID: 26268695

Abstract PR04: CPI-444: A potent and selective inhibitor of A2AR induces antitumor responses alone and in combination with anti-PD-L1 in preclinical and clinical studies

Hexaminolevulinate hydrochloride - CAS# 140898-91-5 60022 PubMed Central PMCID: PMC2849388Hexaminolevulinate hydrochloride, CAS No. 140898 91 5, also known as hexyl 5 aminolevulinate HCl, is the hexyl ester of 5 aminolevulinic acid (ALA) with photodynamic properties. As a precursor of photoactive porphorins, hexyl 5 aminolevulinate induces the endogenous production of the photosensitizer protoporphyrin IX (PPIX) which accumulates selectively in tumor tissue. When exposed to specific wavelengths of light, PPIX is activated and, depending on

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