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(-)-TK216 Size:Contact [email protected] for quotation 7aR)-6-(2-amino-6-ethoxy-9H-purin-9-yl)-7-fluoro-7-methyl-2-(propan-2-yloxy)-hexahydro-2λ⁵-furo[3

SKU: 92276514251

4.4
USD120.00 USD157.00

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Description

7aR)-6-(2-amino-6-ethoxy-9H-purin-9-yl)-7-fluoro-7-methyl-2-(propan-2-yloxy)-hexahydro-2λ⁵-furo[3

CC(C)N(CC)C1N=C(N)C(=NC=1Cl)C(=O)NC(N)=N

is an inhibitor of COX-2 with an IC50 value of 0

Smiles: CC(C)[C@@H]1CC[C@@H](C)CC1=O

A dose of 100 mg/kg at 4 h and again at 2 h before challenge is more effective than a single dose at 2 h

(-)-TK216 Size:Contact [email protected] for quotation 7aR)-6-(2-amino-6-ethoxy-9H-purin-9-yl)-7-fluoro-7-methyl-2-(propan-2-yloxy)-hexahydro-2λ⁵-furo[3( ) TK216 is an enantiomer of TK216 (HY 122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor. ( ) TK216 has anti cancer activity. Product information CAS Number: 1903783 78 7 Molecular Weight: 376. 23 Formula: C19H15Cl2NO3 Chemical Name: 4,7 dichloro 3 [2 (4 cyclopropylphenyl) 2 oxoethyl] 3 hydroxy 2,3 dihydro 1H indol 2 one Smiles: OC1(CC(=O)C2C=CC(=CC=2)C2CC2)C2=C(NC1=O)C(Cl)=CC=C2Cl InChiKey: ZWHNLSHDLKIXOG

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