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Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology
ClH/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15
InChiKey: RHGZQGXELRMGES-UHFFFAOYSA-N
is a highly potent and selective HDAC6 inhibitor with an IC50 of 30 nM toward HDAC6
Masitinib inhibits PDGF-BB-stimulated proliferation and PDGFRα tyrosine phosphorylation with IC50 of 300 nM
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride - CAS# 2341841-02-7 Catalog No.:M11527-10 Targeting myocardial remodelling to developThalidomide 4' oxyacetamide alkyl C2 amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4' oxyacetamide alkyl C2 amine hydrochloride can be used to design the PROTACs. Product information CAS Number: 2341841 02 7 Molecular Weight: 410. 81 Formula: C17H19ClN4O6 Chemical Name: N (2 aminoethyl) 2 {[2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3 dihydro 1H isoindol 4 yl]oxy}acetamide
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