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GRK2-IN-1 Size:Contact [email protected] for quotation Smiles: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO

SKU: 92899119584

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Description

Smiles: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO

InChi: InChI=1S/C22H23ClF3N5O/c1-29(2)22(32)30-8-7-15(11-30)27-21-16-9-13(23)3-5-18(16)31(12-20(25)26)19-6-4-14(24)10-17(19)28-21/h3-6

in disc assays

the chemical structure of acetyl-CoA facilitates the transfer of the acetyl moiety to a variety of acceptor molecules

3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors

GRK2-IN-1 Size:Contact [email protected] for quotation Smiles: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)COGRKs IN 1, Compound 14as, has remarkable potency against and selectivity for G protein coupled receptor kinase 2 GRK2 (IC50=30 nM) and GRK5 (IC50=7. 1 M). GRKs IN 1 is a derivative 14as of paroxetine, shows a 100 fold improvement in cardiomyocyte contractility assays over paroxetine. Product information CAS Number: 2055990 90 2 Molecular Weight: 452. 48 Formula: C24H25FN4O4 Chemical Name: 5 [(3S,4R) 3 [(2H 1,3 benzodioxol 5 yloxy)methyl]piperidin 4

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