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10)13-3-5(7)6(8)4-14-16(2
PubMed PMID: 10511444
7-naphthyridin-4-yl)-2-6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2
BAY-87-2243 markedly decreased nuclear HIF-1α expression and pimonidazole hypoxic fraction already after 3 days of drug treatment
It binds to BRPF1B with a Kd of 13 nM (ITC)
PROTAC BET degrader-2 EE788 10)13-3-5(7)6(8)4-14-16(2PROTAC BET degrader 2 is a highly potent degrader of Bromodomain and Extra Terminal (BET) proteins with an IC50 value of 9. 6 nM in cell growth inhibition in the RS4; 11 cells and capable of achieving tumor regression. Product information CAS Number: 2093388 33 9 Molecular Weight: 770. 84 Formula: C41H42N10O6 Chemical Name: 4 [(3 cyclopropyl 1 ethyl 1H pyrazol 5 yl)amino] 7 (3, 5 dimethyl 1, 2 oxazol 4 yl) N {3 [2 (2, 6 dioxopiperidin 3 yl) 1 oxo 2, 3
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