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MPI 0479605
67(2):83-92
Temsirolimus (100 ng/mL) potently inhibits proliferation and induces apoptosis in primary human lymphoblastic leukemia (ALL) cells
CAS Number: 189232-42-6
Selective Inhibitor of the Protein Methyltransferase DOT1L for Use in the Treatment of MLL-Rearranged Leukemia
Fingolimod hydrochloride 7903 MPI 0479605Fingolimod hydrochloride (FTY720), an analog of sphingosine, is a potent sphingosine 1 phosphate (S1P) receptors modulator. Fingolimod hydrochloride is phosphorylated by sphingosine kinases, particularly by SK2, and then binds S1PR1, 3, 4, and 5. Fingolimod hydrochloride induces the internalization of S1P1, and consequently, inhibits S1P activity. Fingolimod hydrochloride also is a pak1 activator Product information CAS Number: 162359 56 0 Molecular