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(2015) Science
and non-toxic natural product may finds its application in the antibacterial drug development for treating multidrug-resistant Gram negative infections
Triazolotriazine derivatives as a2a receptor antagonists
It suppresses growth of Haemonchus and Trichomonas and decreases viability of myeloma cells
20(11):20659-68
YKL-5-124 TFA Catalog No.:M14492-2 (2015) ScienceYKL 5 124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53. 5 nM and 9. 7 nM for CDK7 and CDK7 Mat1 CycH, respectively. YKL 5 124 TFA is >100 fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL 5 124 TFA induces a strong cell cycle arrest, inhibits E2F driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status. Product information
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