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A nonsteroidal glucocorticoid receptor antagonist
including those with neutropenia due to cancer chemotherapy
Smiles: CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C21
InChi: InChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H
Saracatinib (AZD0530)
3'-Hydroxypterostilbene - CAS# 475231-21-1 Catalog No.:M12494-10 A nonsteroidal glucocorticoid receptor antagonist3' Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9. 0, 40. 2, and 70. 9 M for COLO 205, HCT 116, and HT 29 cells, respectively) by inducing apoptosis and autophagy. 3' Hydroxypterostilbene inhibits the PI3K Akt mTOR p70S6K, and p38MAPK pathways and activates the ERK1 2, JNK1 2 MAPK pathways. Product information CAS Number: 475231 21 1 Molecular Weight: 272. 30 Formula: