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25 or 50 μM) can inhibit the FGFR2 kinase activity in a dose-dependent manner
InChiKey: INBGSXNNRGWLJU-ZHHJOTBYSA-N
InChiKey: CYOVYGWNDHLPBF-UHFFFAOYSA-N
rauwolscine is determined to have relatively high affinity for the human receptor (Ki human=14
Chemical Name: tetralithium(1+) ({[(2R
APG-1387 l D6 Nitrate 25 or 50 μM) canAPG 1387, a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins (XIAP, cIAP 1, cIAP 2, and ML IAP). APG 1387 induces degradation of cIAP 1 and XIAP proteins, as well as caspase 3 activation and PARP cleavage, which leads to apoptosis. APG 1387 can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma. Product information CAS Number: 1570231 89 8 Molecular Weight: 1157.
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