orally available and brain penetrant OX2R antagonist with a pKi of 7
35(11):2129-34
MCF7 and MiaPaCa-2 cells) treatment markedly reduces cell viability in a dose-dependent and a time-dependent association in K562
8 μM (LoVo) at 24 hours
In an isolated perfused working rat heart model
Hernandezine Size:Contact [email protected] for quotation orally available and brain penetrantHernandezine (Hernandesine) is isolated from T. flavum L. Product information CAS Number: 6681 13 6 Molecular Weight: 652. 78 Formula: C39H44N2O7 Chemical Name: (1S,14S) 9,19,20,21,25 pentamethoxy 15,30 dimethyl 7,23 dioxa 15,30 diazaheptacyclo[22. 6. 2. 2,. 1,. 1,. 0,. 0,]hexatriaconta 3,5,8,10,12(34),18(33),19,21,24,26,31,35 dodecaene Smiles: CN1CCC2=C3[C@@H]1CC1=CC(OC4C=CC(C[C@H]5C6=CC(OC3=C(OC)C(OC)=C2OC)=C(C=C6CCN5C)OC)=CC=4)=C(C=C1)OC InChiKey: