Pay in 4 interest-free payments of $27.00 Learn more
Ships within 48 hours · Estimated delivery Aug 24 - Aug 29
suggesting that VX-745 can inhibit paracrine multiple myeloma (MM) cell growth in the BM milieu and overcome cell adhesion-related drug resistance
InChi: InChI=1S/C25H21N3O/c1-18-15-22(12-14-27-18)20-6-4-19(5-7-20)16-25(29)28-24-10-8-21(9-11-24)23-3-2-13-26-17-23/h2-15
of deubiquitinating enzyme (DUB) activity
Andersen JN
KY1220 dose dependently decreases Wnt3a-CM-induced TOPflash reporter activation and mRNA expression of Wnt target genes CCND1 and MYC in HEK293 cells
SNS-314 Size:2mg solid suggesting that VX-745 can inhibitSNS 314 is a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS 314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Product information CAS Number: 1057249 41 8
US$ 75.00
US$ 800.00
US$ 1550.00
US$ 197.50
US$ 650.00