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10(12):4235-4246
The Shogaol ([6]-Shogaol) decreases the diethylnitrosamine (DEN)-mediated elevations of serum aspartate transaminase and alanine transaminase as well as the DEN-induced hepatic lipid peroxidation
28-decaoxo-2
Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ
IhERG inhibition by KB-R7943 exhibits both time- and voltage-dependence but shows no preference for inactivated over activated channels
AM-2394 II Degrader-3 10(12):4235-4246AM 2394 is a structurally distinct glucokinase activator (GKA). AM 2394 activates glucokinase (GK) with an EC50 of 60 nM. Product information CAS Number: 1442684 77 6 Molecular Weight: 423. 47 Formula: C22H25N5O4 Chemical Name: 1 [6' (2 hydroxy 2 methylpropoxy) 4 [(5 methylpyridin 3 yl)oxy] [3,3' bipyridin] 6 yl] 3 methylurea Smiles: CC1C=C(C=NC=1)OC1C=C(NC(=O)NC)N=CC=1C1C=NC(=CC=1)OCC(C)(C)O InChiKey: QUISANLDBDCMPD UHFFFAOYSA N InChi: InChI=1S