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BI-9564 - BRD9 Bromodomain Inhibitor. CAS# 1883429-22-8 size:2 mg solid Dacinostat (10 and 20 nM)

SKU: 95049401656

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Description

Dacinostat (10 and 20 nM) suppresses proliferation of AML fusion protein-expressing 32D cells

PRMT6 and PRMT8

(1992) Proc Natl Acad Sci USA

Chemical Name: (S)-N-(bis(4-fluorophenyl)methyl)-1-(2-(2-ethyl-2-isobutyramidobutanamido)-5-guanidinopentanamido)cyclopentanecarboxamide

The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression

BI-9564 - BRD9 Bromodomain Inhibitor. CAS# 1883429-22-8 size:2 mg solid Dacinostat (10 and 20 nM)BI 9564, CAS No. 1883429 22 8, is a potent and selective inhibitor of BRD9 and BRD7 bromodomains (Kds = 14. 1 and 239 nM; IC50s = 75 nM and 3. 4 M, respectively). BI 9564 is useful in further exploring BRD9 bromodomain biology in both in vitro and in vivo settings. Selective inhibitors of bromodomain containing protein 9 (BRD9) may have therapeutic potential in the treatment of human malignancies and inflammatory diseases. Product information CAS

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