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FM26 Size:Contact [email protected] for quotation decreases cell viability (IC50 =

SKU: 95276143266

4.3
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Description

decreases cell viability (IC50 = 2142 nM) and elicits the caspase 3/7 activity (EC50 = 2288 nM) in Colo-205 cells

11a-tetramethyl-1-(prop-1-en-2-yl)-icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylic acid

and reduces synaptic toxicity and lowers amyloid plaques in an Alzheimer's disease mouse model

19-42)25(37)11-14-40(26

InChi: InChI=1S/C22H27F2N3O/c1-22(23

FM26 Size:Contact [email protected] for quotation decreases cell viability (IC50 =FM26 (compound 25) is a potent and allosteric retinoic acid receptor related orphan receptor t (RORt) inverse agonists with an IC50 of 264 nM. FM26 has a distinct isoxazole chemotype and effectively reduces IL 17a mRNA production in EL4 cells. Product information CAS Number: 2407981 35 3 Molecular Weight: 461. 82 Formula: C22H15ClF3N3O3 Chemical Name: 4 [({3 [2 chloro 6 (trifluoromethyl)phenyl] 5 (1H pyrrol 3 yl) 1,2 oxazol 4 yl}methyl)amino]benzoic

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