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Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
17-trihydroxy-14
This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies
InChi: InChI=1S/C27H28N6O/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33/h4-11
eventually leading to cellular activation
AP-1/NF-κB activation inhibitor 1 Size:Contact [email protected] for quotation Rilmenidine attenuates toxicity of polyglutamineAP 1 NF B activation inhibitor 1 is a potent AP 1 and NF B mediated transcriptional activation inhibitor (IC50=1 M), without blocking basal transcription driven by the actin promoter. AP 1 NF B activation inhibitor 1 has a similar inhibitory effect on the production of IL 2 and IL 8 levels in stimulated cells. Product information CAS Number: 188936 12 1 Molecular Weight: 344. 25 Formula: C13H11F3N4O4 Chemical Name: ethyl 4 [(3 methyl 2,5 dioxo 2,5
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