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InChiKey: QXWYKJLNLSIPIN-JGVFFNPUSA-N
Smiles: O[C@@H]1CC[C@H](CC1)SCC1NC(=O)C2C(F)=CC(=CC=2N=1)OCC1CC1
9(3):268-273
Pizarro JG
for 8 hours
FK 866 hydrochloride emodin InChiKey: QXWYKJLNLSIPIN-JGVFFNPUSA-NFK 866 hydrochloride is an inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 values ranging between 0. 09nM and 27. 2nM . NAD plays a vital role in numerous biochemical and biologic processes. Targeting NAD synthesis is thought to be a selective manner to kill cancer cells since cancer cells have a higher rate of NAD turnover compared with normal cells. In the vitro MTT assay using a panel of 41 human hematologic cancer cell