and cardiovascular disorders
due to increases in side-effects with no cardiovascular benefit
ClH/c1-13(2)10-20-16-8-9-19-18(23-16)21-11-15-12-24-17(22-15)14-6-4-3-5-7-14
THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3
InChi: InChI=1S/C21H22FN3O/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13/h3-7
H4 Receptor antagonist 1 RAS and cardiovascular disordersH4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM. Product information CAS Number: 848217 00 5 Molecular Weight: 316. 79 Formula: C16H17ClN4O Chemical Name: 12 chloro 4 methyl 6 (4 methylpiperazin 1 yl) 8 oxa 3,5 diazatricyclo[7. 4. 0. 0,]trideca 1(13),2,4,6,9,11 hexaene Smiles: CN1CCN(CC1)C1N=C(C)N=C2C=1OC1=CC=C(Cl)C=C12 InChiKey: GUJLUPNSRRNJKP UHFFFAOYSA N InChi: InChI=1S C16H17ClN4O c1