PG01 Catalog No.:M16477-C 15(22)23)6-11(19)14(12)21/h1-5

15(22)23)6-11(19)14(12)21/h1-5

InChiKey: MAUCONCHVWBMHK-UHFFFAOYSA-N

(1992) Proc Natl Acad Sci USA

InChiKey: GECHUMIMRBOMGK-UHFFFAOYSA-N

39-undecahydroxy-2

PG01 Catalog No.:M16477-C 15(22)23)6-11(19)14(12)21/h1-5PG01 is a potent CFTR Cl channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D (CFTR mutants) with Kd values of 0. 22 M, 0. 45 M and 1. 94 M, respectively. PG01 is also effective on F508 (Ka of 0. 3 M). PG01 increases F508 CFTR Cl current after adding Forskolin. Product information CAS Number: 853138 65 5 Molecular Weight: 439. 55 Formula: C28H29N3O2 Chemical Name: 2 [2 (1H indol 3 yl) N